Welcome From The Chair

Message From The Director of Graduate Admissions

Faculty

Tanyel Kiziltepe, Assistant Research Professor

Education
B.S. Chemistry, Bilkent University, Turkey (1998)
Ph.D. Biological Chemistry, Massachusetts Institute of Technology, MA (2004)

Professional Experience
Postdoc Fellow, Dana Farber Cancer Institute, MA (2005-2007)
Faculty, Harvard Medical School, MA (2005-2007)
Scientist, Cerulean Pharmaceuticals, MA (2007-2008)
Assistant Research Professor, University of Notre Dame, IN (2008-present)

Research Interests

Pre-clinical drug validation in cancers
Nanoparticle based drug delivery
Biochemical stabilization of biomolecular therapeutics

Publications

Kiziltepe T, Hideshima T, Catley L, Raje N, Yasui H, Vallet S, Okawa Y, Ikeda H, Ishitsuka K, Shiraishi N, Chauhan D, Anderson KC. 5-Azacytidine, a DNA Methyltransferase Inhibitor, Induces ATR Mediated DNA Double Strand Break Responses, Apoptosis, and Synergistic Cytotoxicity with Doxorubicin and Bortezomib against Multiple Myelo. Mol Cancer Ther., 6(6):1718-27, 2007.

Kiziltepe T, Hideshima T, Ishitsuka K, Ocio EM, Raje N, Catley L, Li CQ, Trudel LJ, Yasui H, Vallet S, Kutok JL, Chauhan D, Mitsiades CS, Saavedra JE, Wogan GE, Keefer LK, Shami PJ, and Anderson KC. JS -K, a GST-Activated Nitric Oxide Generator, Induces DNA Double Strand Breaks, activates DNA Damage Response Pathways, and Induces Apoptosis, in vitro and in vivo in Human Multiple Myeloma Cells. Blood, 110(2):709-18, 2007.

Sengupta S, Eavarone D, Capila I, Zhao G, Watson N, Kiziltepe T, Sasisekharan R. Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system. Nature, 436(7050):568-72, 2005.

Hideshima T, Chauhan D, Kiziltepe T, Ikeda H, Okawa Y, Podar K, Raje N, Protopopov A, Munshi NC, Richardson PG, Carrasco RD, Anderson KC. Biologic sequelae of IκB kinase (IKK) inhibition in multiple myeloma: therapeutic implications.. Blood, 113 (21):5228-36, 2009.

Awards

Fulbright Fellowship for Doctoral Studies

Given on October 1, 1999

Pharmion Fellowship

Given on October 1, 2005

Multiple Myeloma Research Foundation Fellows' Award

Given on October 1, 2006

Doug Yearley Merit Award

Given on October 1, 2008

Courses

No courses have been added yet.

Images

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