Home > Seminars > Marianthi Ierapetritou

Marianthi Ierapetritou


10/8/2019 at 12:30PM


10/8/2019 at 1:30PM


127 Nieuwland hall
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Continuous manufacturing (CM) has been recognized as an emerging technology by the US Food and Drug Administration (FDA) and other regulatory agents around the world for its potential to improve agility, flexibility, and robustness in pharmaceutical manufacturing which is important for solving the drug shortage problems.


Pharmaceutical companies are actively working on implementing continuous processing technology for both legacy and new products. While approaches to implement CM technology may vary among practitioners, a consensus is rapidly emerging regarding the importance of understanding process dynamics to achieve reliable process performance and ensure acceptable product quality. In recent years, a growing number of industrial and academic research groups have examined the dynamics of continuous pharmaceutical equipment using established process systems engineering methods.

Continuous production requires detailed process understanding in terms of the evolution of all critical material properties as a function of its operating parameters and environmental conditions. Once process knowledge is translated into models, process systems engineering tools allows the design, analysis and optimization of continuous integrated processes. The major challenges to achieve this goal, and highlights of the work that has been performed in our lab in the recent years to address these problems will be covered in the talk.

Seminar Speaker:

Marianthi Ierapetritou

Marianthi Ierapetritou

University of Delaware

Marianthi Ierapetritou is the Bob and Jane Gore Centennial Professor in the Department of Chemical and Biomolecular Engineering at University of Delaware. Prior to that she has been a Distinguished Professor in the Department of Chemical and Biochemical Engineering at Rutgers University. During the last year at Rutgers University she led the efforts of the university advancing the careers in STEM for women at Rutgers as an Associate Vice President of the University.

Dr. Ierapetritou’s research focuses on the following areas: 1) process operations; (2) design and synthesis of flexible production systems focusing on pharmaceutical manufacturing; 3) energy and sustainability process modeling and operations; and 4) modeling of biopharmaceutical production. Her research is supported by several federal (FDA, NIH, NSF, ONR, NASA) and industrial (BMS, J&J, GSK, PSE, Bosch, Eli Lilly) grants.

Among her accomplishments are the appointment as the Gore Centennial Professor in 2019, the promotion to distinguished professor at Rutgers University in 2017, the 2016 Computing and Systems Technology (CAST) division Award in Computing in Chemical Engineering which is the highest distinction in the Systems area of the American Institute of Chemical Engineers (AIChE), the Award of Division of Particulate Preparations and Design (PPD) of The Society of Powder Technology, Japan; the Outstanding Faculty Award at Rutgers; the Rutgers Board of Trustees Research Award for Scholarly Excellence; and the prestigious NSF CAREER award. She has also been appointed as a Consultant to the FDA under the Advisory Committee for Pharmaceutical Science and Clinical Pharmacology, elected as a fellow of AICHE and as a Director in the board of AIChE. She has more than 250 publications, and has been an invited speaker to numerous national and international conferences.

Dr. Ierapetritou obtained her BS from The National Technical University in Athens, Greece, her PhD from Imperial College (London, UK) in 1995 and subsequently completed her post-doctoral research at Princeton University (Princeton, NJ).

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