O'Hara Professor of Chemistry and Biochemistry; Associate Vice President for Research
Concurrent Professor, Chemical and Biomolecular Engineering
443 Stephan Chemistry Hall
Areas of Interest
Research in Prof. Clark’s laboratory focuses on determining the behaviors of linear biopolymers (polypeptides) in water.
For example, why are some polypeptide sequences able to fold to a specific 3D structure, whereas others remain intrinsically disordered?
What determines the rate (kinetics) of protein folding, and how does the cellular environment modulate protein folding mechanisms?
The Clark lab develops model systems and experimental and computational methods to probe protein folding.